David Hume be damned, the answer is "yes" according to Sam Harris, in The Moral Landscape: How Science Can Determine Human Values (Free Press, 2010). Harris argues that all values reduce to "facts" that science can provide.
Harris is a utilitarian, seeking to reduce "needless human suffering." In his view, science allows "us"—that is, well-educated liberal Westerners--to decide on the meaning of "moral progress." It should be clear, he argues, what human flourishing means and that we can adopt a definition and measurement using scientific methods. In short, there is an absolute moral standard of right and wrong, as illuminated by the "science" of human well-being.
Aside from Harris' arrogance, there is a huge dose of condescension. There is no fair conception here of what the human experience means in non-Western cultures. To Harris, the measure of human progress appears to be externally-driven by caloric intake and clothes (he rails against the "sacks" that Islamic women wear). I haven't read the book, but I am curious if Harris is aware of Nozick's Experience Machine that could make and keep us perfectly pleasured. Is that an ideal life? It would seem so to Harris.
If you don't want to buy the book, you can get the essence of his message in this TED talk.